Peter Simon Selected Research

Hereditary pancreatitis

3/2015	Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis.
11/2013	Evidence of pancreatic neuropathy and neuropathic pain in hereditary chronic pancreatitis.
4/2009	Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism.
10/2008	Local clustering of PRSS1 R122H mutations in hereditary pancreatitis patients from Northern Germany.
3/2004	Clinical and genetic characteristics of hereditary pancreatitis in Europe.
2/2002	Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen.

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Peter Simon Research Topics

Disease

18	Chronic Pancreatitis 08/2019 - 06/2006
11	Pancreatitis 10/2018 - 02/2002
6	Pain (Aches) 05/2019 - 01/2013
6	Hereditary pancreatitis 03/2015 - 02/2002
5	Osteoarthritis 01/2021 - 03/2015
5	Pancreatic Neoplasms (Pancreatic Cancer) 01/2017 - 01/2011
4	Neoplasms (Cancer) 01/2016 - 06/2006
2	Shoulder Fractures 08/2020 - 06/2019
2	Humeral Fractures 07/2020 - 03/2018
2	Acute Necrotizing Pancreatitis 12/2018 - 12/2003
2	Cachexia 05/2016 - 07/2012
2	Weight Loss (Weight Reduction) 03/2014 - 07/2012
2	Cystic Fibrosis (Mucoviscidosis) 01/2011 - 06/2006
2	Sepsis (Septicemia) 01/2010 - 01/2008
1	Osteophyte 01/2022
1	Fistula 08/2019
1	Hemorrhage 08/2019
1	Rotator Cuff Tear Arthropathy 06/2019
1	Joint Diseases (Joint Disease) 06/2019
1	Pancreatic Pseudocyst 12/2018
1	Rotator Cuff Injuries 12/2018
1	Arthritis (Polyarthritis) 12/2018
1	Osteoporosis 10/2018
1	Metabolic Bone Diseases (Osteopenia) 10/2018
1	Bone Cysts (Bone Cyst) 05/2018
1	Wrist Fractures 08/2017
1	Reinfection 07/2017
1	Infections 07/2017
1	Pathologic Processes 06/2017
1	Inflammation (Inflammations) 01/2017
1	Vitamin D Deficiency 11/2016
1	Weight Gain 07/2016
1	Exocrine Pancreatic Insufficiency 03/2014
1	Flatulence 03/2014
1	Intractable Pain 11/2013
1	Chronic Obstructive Pulmonary Disease (COPD) 10/2013
1	Dyspnea (Shortness of Breath) 08/2013

Drug/Important Bio-Agent (IBA)

10	TrypsinogenIBA 10/2018 - 02/2002
5	Lipase (Acid Lipase)FDA Link 01/2017 - 01/2013
5	Kazal Pancreatic Trypsin InhibitorIBA 07/2015 - 06/2006
4	TrypsinIBA 07/2015 - 02/2002
3	Galactoside 2-alpha-L-fucosyltransferase (Fucosyltransferase 2)IBA 02/2016 - 04/2015
3	Proteins (Proteins, Gene)FDA Link 07/2015 - 06/2006
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2008 - 12/2003
2	VitaminsIBA 10/2018 - 11/2016
2	theasinensin AIBA 05/2018 - 05/2015
2	EstersIBA 01/2017 - 01/2013
2	Carnitine (L-Carnitine)FDA LinkGeneric 05/2016 - 07/2012
2	Blood Group Antigens (Blood Groups)IBA 07/2015 - 04/2015
2	Peptide Hydrolases (Proteases)FDA Link 05/2015 - 01/2013
2	EnzymesIBA 03/2014 - 01/2013
2	CalciumIBA 01/2013 - 02/2002
2	SmokeIBA 01/2011 - 01/2010
1	Saline SolutionIBA 08/2020
1	Hemoglobins (Hemoglobin)IBA 08/2020
1	Tranexamic Acid (AMCA)FDA Link 08/2020
1	RCA IIIBA 06/2019
1	MetalsIBA 12/2018
1	PlasticsIBA 12/2018
1	Vitamin D FDA LinkGeneric 10/2018
1	Protein Isoforms (Isoforms)IBA 10/2018
1	CoagulaseIBA 07/2017
1	Vitamin A (Retinol)FDA LinkGeneric 11/2016
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 05/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	Pharmaceutical PreparationsIBA 01/2016
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2016
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2016
1	tyrosine receptor (receptor, tyrosine)IBA 01/2016
1	Phosphotransferases (Kinase)IBA 01/2016
1	Ethanol (Ethyl Alcohol)IBA 07/2015
1	Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA 07/2015
1	N-(4-aminophenethyl)spiroperidol (NAPS)IBA 07/2015
1	Claudin-2IBA 07/2015
1	Aldehyde DehydrogenaseIBA 07/2015
1	Protease Inhibitors (Protease Inhibitor)IBA 05/2015
1	NucleotidesIBA 03/2015
1	Pancreatic Elastase (Elastase)IBA 03/2014
1	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 10/2013
1	polysialic acidIBA 10/2013
1	MagnesiumIBA 01/2013

Therapy/Procedure

12	Arthroplasty 01/2021 - 03/2015
5	Length of Stay 01/2017 - 01/2013
4	Therapeutics 08/2019 - 06/2006
2	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2022 - 07/2013
2	Hemiarthroplasty 07/2020 - 03/2018
2	Braces 08/2017 - 07/2013
2	Conservative Treatment 07/2016 - 12/2003
2	Parenteral Nutrition 12/2004 - 12/2003
2	Enteral Nutrition (Feeding, Tube) 12/2004 - 12/2003
1	Operative Surgical Procedures 08/2019
1	Surgical Instruments (Clip) 08/2019
1	Stents 12/2018
1	Bone Transplantation (Bone Grafting) 09/2017
1	Replantation 07/2017
1	Operative Time 06/2017
1	Reoperation 06/2017
1	Pancreaticoduodenectomy 07/2016
1	Patient Readmission 05/2015
1	Pancreatectomy 11/2013